Publications

Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice.

Date Published: January 7, 2012
Mycolic acids are attractive diagnostic markers for tuberculosis (TB) infection because they are bacteria-derived, contain information about bacterial species, modulate host-pathogen interactions and are chemically inert. Here, we present a novel approach based on mass spectrometry. Quantification of specific precursor → fragment transitions of approximately 2000 individual mycolic acids (MAs)…
Courtesy of the U.S. National Library of Medicine